Micro GLP-1.

A plant extract clinically studied to lower body fat and naturally elevate GLP-1. Known in the research as CQR-300. 300 mg in every stick.

A glass dish of pink Micro GLP-1 powder, a glass of water and a Calla stick on deep burgundy
Per stick
300 mg
Routine
Once a day
Mechanism
Your own GLP-1
Calories
0
Clinical results Change vs placebo
Body fat −10.9%
Measure
Percent body fat
Source
Medicina, 2026 ¹
Active GLP-1 +321%
Measure
Circulating active GLP-1
Source
Medicina, 2026 ¹
Energy intake −17.5%
Measure
Daily calories eaten
Source
Medicina, 2026 ¹

¹ Medicina 62(1):41, 2026. Randomized, placebo-controlled, 16 weeks, 248 adults, 300 mg CQR-300 per day. A study of the ingredient, not of Calla.

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How it works.

  1. 01

    Your gut makes GLP-1.

    It is released when you eat. It is the body’s main signal that a meal is enough.

  2. 02

    CQR-300 raises it.

    In the trial, active GLP-1 rose 321% over 16 weeks, while DPP-4, the enzyme that breaks it down, fell 17.8%. Your own hormone, not a synthetic one.

  3. 03

    More GLP-1, less noise.

    Fuller sooner. Less food noise between meals. A calorie deficit that is easier to hold.

FAQ

Is it a GLP-1 medication?

No. Not a prescription GLP-1 medication, and not a substitute for one. Not an injection; a powder you stir into water. Not a replacement for your doctor. If you take medication or have a condition, ask first.

How does CQR-300 raise GLP-1?

Two ways, according to the trial. More GLP-1 is released, and less of it is broken down: activity of DPP-4, the enzyme that clears GLP-1, fell 17.8%. The researchers propose other pathways too, from appetite signalling to how starch is digested, and those are still being mapped. What is established is the outcome: higher active GLP-1, lower energy intake and lower body fat over 16 weeks.

Is it safe?

CQR-300 is a standardized extract of Cissus quadrangularis. It is recognized as safe for use in food in the United States and has been studied in placebo-controlled trials. Talk to your physician first if you are pregnant, nursing, under 18, or taking medication.

Can I take it alongside a prescription GLP-1?

Ask your prescriber. Micro GLP-1 is not a drug, but anything that touches appetite and metabolism belongs in that conversation.

How long before I notice anything?

The energy is immediate. The trial measured Micro GLP-1 over 16 weeks of daily use, which is why Calla comes thirty to a box.

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