Micro GLP-1.
A plant extract clinically studied to lower body fat and naturally elevate GLP-1. Known in the research as CQR-300. 300 mg in every stick.

- Per stick
- 300 mg
- Routine
- Once a day
- Mechanism
- Your own GLP-1
- Calories
- 0
- Measure
- Percent body fat
- Source
- Medicina, 2026 ¹
- Measure
- Circulating active GLP-1
- Source
- Medicina, 2026 ¹
- Measure
- Daily calories eaten
- Source
- Medicina, 2026 ¹
¹ Medicina 62(1):41, 2026. Randomized, placebo-controlled, 16 weeks, 248 adults, 300 mg CQR-300 per day. A study of the ingredient, not of Calla.
Shop Calla
How it works.
-
01
Your gut makes GLP-1.
It is released when you eat. It is the body’s main signal that a meal is enough.
-
02
CQR-300 raises it.
In the trial, active GLP-1 rose 321% over 16 weeks, while DPP-4, the enzyme that breaks it down, fell 17.8%. Your own hormone, not a synthetic one.
-
03
More GLP-1, less noise.
Fuller sooner. Less food noise between meals. A calorie deficit that is easier to hold.
FAQ
Is it a GLP-1 medication?
No. Not a prescription GLP-1 medication, and not a substitute for one. Not an injection; a powder you stir into water. Not a replacement for your doctor. If you take medication or have a condition, ask first.
How does CQR-300 raise GLP-1?
Two ways, according to the trial. More GLP-1 is released, and less of it is broken down: activity of DPP-4, the enzyme that clears GLP-1, fell 17.8%. The researchers propose other pathways too, from appetite signalling to how starch is digested, and those are still being mapped. What is established is the outcome: higher active GLP-1, lower energy intake and lower body fat over 16 weeks.
Is it safe?
CQR-300 is a standardized extract of Cissus quadrangularis. It is recognized as safe for use in food in the United States and has been studied in placebo-controlled trials. Talk to your physician first if you are pregnant, nursing, under 18, or taking medication.
Can I take it alongside a prescription GLP-1?
Ask your prescriber. Micro GLP-1 is not a drug, but anything that touches appetite and metabolism belongs in that conversation.
How long before I notice anything?
The energy is immediate. The trial measured Micro GLP-1 over 16 weeks of daily use, which is why Calla comes thirty to a box.
More on the science.
Short, sourced pages on the questions people ask us most.
Get first access.
Be first when Calla ships, and first to read the studies as we publish them.